Amflutizole

Amflutizole
Clinical data
ATC code
  • none
Identifiers
IUPAC name
  • 4-Amino-3-[3-(trifluoromethyl)phenyl]-1,2-thiazole-5-carboxylic acid
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
ChEMBL
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC11H7F3N2O2S
Molar mass288.24 g·mol−1
3D model (JSmol)
SMILES
  • FC(F)(F)c1cccc(c1)c2nsc(c2N)C(=O)O
InChI
  • InChI=1S/C11H7F3N2O2S/c12-11(13,14)6-3-1-2-5(4-6)8-7(15)9(10(17)18)19-16-8/h1-4H,15H2,(H,17,18) Y
  • Key:KVMCEGAWQYTFKC-UHFFFAOYSA-N Y
  (verify)

Amflutizole is a xanthine oxidase inhibitor[1] used for the treatment of gout.

References

  1. ^ O'Regan MH, Smith-Barbour M, Perkins LM, Cao X, Phillis JW (October 1994). "The effect of amflutizole, a xanthine oxidase inhibitor, on ischemia-evoked purine release and free radical formation in the rat cerebral cortex". Neuropharmacology. 33 (10): 1197–201. doi:10.1016/S0028-3908(05)80010-3. PMID 7862255. S2CID 37262919.
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