Clefamide

Clefamide
Clinical data
Trade namesMebinol
ATC code
Identifiers
IUPAC name
  • 2,2-Dichloro-N-(2-hydroxyethyl)-N-[[4-(4-nitrophenoxy)phenyl]methyl]
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.020.631
Chemical and physical data
FormulaC17H16Cl2N2O5
Molar mass399.22 g·mol−1
3D model (JSmol)
SMILES
  • ClC(Cl)C(=O)N(CCO)Cc2ccc(Oc1ccc(cc1)[N+]([O-])=O)cc2
InChI
  • InChI=1S/C17H16Cl2N2O5/c18-16(19)17(23)20(9-10-22)11-12-1-5-14(6-2-12)26-15-7-3-13(4-8-15)21(24)25/h1-8,16,22H,9-11H2 Y
  • Key:ODCUSWJXZDHLKV-UHFFFAOYSA-N Y
  (verify)

Clefamide (trade name Mebinol) is an antiprotozoal agent that was used to treat amoebiasis in the 1960s.[1] There is no evidence for any later use of the drug.

References

  1. ^ Rodrigues LD, Jafferian PA, Vilella M, Costa AA, de Mello EB (November 1968). "[Comparative study on 3 amebicides: teclozine, clefamide and a combination of clefamide and iodo-chloro-oxyquinolines and streptomycin]". Hospital. 74 (5): 1563–73. PMID 5305335.
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