Pafenolol

Pafenolol
Names
IUPAC name
1-[2-[4-[2-Hydroxy-3-(propan-2-ylamino)propoxy]phenyl]ethyl]-3-propan-2-ylurea
Identifiers
CAS Number
3D model (JSmol)
ChemSpider
PubChem CID
InChI
  • InChI=1S/C18H31N3O3/c1-13(2)20-11-16(22)12-24-17-7-5-15(6-8-17)9-10-19-18(23)21-14(3)4/h5-8,13-14,16,20,22H,9-12H2,1-4H3,(H2,19,21,23)
  • InChI=1/C18H31N3O3/c1-13(2)20-11-16(22)12-24-17-7-5-15(6-8-17)9-10-19-18(23)21-14(3)4/h5-8,13-14,16,20,22H,9-12H2,1-4H3,(H2,19,21,23)
    Key: PKWZWSXSCKVUJB-UHFFFAOYAJ
SMILES
  • CC(C)NCC(COC1=CC=C(C=C1)CCNC(=O)NC(C)C)O
Properties
Chemical formula
 C18H31N3O3
Molar mass 337.464 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

Pafenolol is a beta adrenergic receptor antagonist.[1]

References

  1. ^ Lennernäs, H; Regårdh, CG (1993). "Dose-dependent intestinal absorption and significant intestinal excretion (exsorption) of the beta-blocker pafenolol in the rat". Pharmaceutical Research. 10 (5): 727–31. doi:10.1023/a:1018916017723. PMID 8100631. S2CID 30351822.


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