Sofalcone |
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| AHFS/Drugs.com | International Drug Names |
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Routes of
administration | Oral |
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| ATC code | |
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| Legal status |
- In general: ℞ (Prescription only)
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[5-[(3-Methylbut-2-en-1-yl)oxy]-2-((2E)-3-{4-[(3-methylbut-2-en-1-yl)oxy]phenyl}prop-2-enoyl)phenoxy]acetic acid
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| CAS Number | |
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| PubChem CID | |
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| ChemSpider | |
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| UNII | |
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| KEGG | |
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| ChEBI | |
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| CompTox Dashboard (EPA) | |
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| Formula | C27H30O6 |
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| Molar mass | 450.531 g·mol−1 |
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| 3D model (JSmol) | |
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CC(=CCOC1=CC=C(C=C1)C=CC(=O)C2=C(C=C(C=C2)OCC=C(C)C)OCC(=O)O)C
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InChI=1S/C27H30O6/c1-19(2)13-15-31-22-8-5-21(6-9-22)7-12-25(28)24-11-10-23(32-16-14-20(3)4)17-26(24)33-18-27(29)30/h5-14,17H,15-16,18H2,1-4H3,(H,29,30)/b12-7+ N Key:GFWRVVCDTLRWPK-KPKJPENVSA-N N
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| NY (what is this?) (verify) |
Sofalcone (INN) is an oral gastrointestinal medication used in Japan.[1] It is a synthetic analog of sophoradin,[2] a type of natural phenol found in Sophora tonkinensis, an herb used in traditional Chinese medicine.
References
- ^ "Sofalcone". drugs.com.
- ^ Konturek SJ, Mrzozowski T, Drozdowicz D, Pawlik W, Sendur R (August 1987). "Gastroprotective and ulcer healing effects of solon, a synthetic flavonoid derivative of sophoradin". Hepatogastroenterology. 34 (4): 164–70. PMID 3478294.
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| Chalconoids | |
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| Chalconoid glycosides |
- Carthamin
- Marein
- okanin 3,4,3′-trimethyl ether 4′-glucoside
- okanin 4-methyl ether 4′-glucoside
- okanin 4-methyl ether 4′-glucoside monoacetate
- Okanin 3,4-dimethyl ether 4′-glucoside
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| Acylated chalconoids |
- Licochalcone A
- Sophoradin (prenylated)
- Tephrospinosin (3′,5′-diisopentenyl-2′,4′-dihydroxychalcone) (prenylated)
- Xanthohumol (prenylated)
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| O-methylated chalconoids |
- Cardamomin
- Flavokawin B
- Okanin 3,4,3′,4′-tetramethyl ether
- Pashanone (2',6'-Dihydroxy-3',4'-dimethoxychalcone)
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| Flavokavains |
- Flavokavain A
- Flavokavain B
- Flavokavain C
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| Synthetic | |
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