Trifluoromethylaminoindane

Trifluoromethylaminoindane
Identifiers
IUPAC name
  • 5-(trifluoromethyl)-2,3-dihydro-1H-inden-2-amine
CAS Number
PubChem CID
ChemSpider
UNII
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC10H10F3N
Molar mass201.192 g·mol−1
3D model (JSmol)
SMILES
  • C1C(CC2=C1C=CC(=C2)C(F)(F)F)N
InChI
  • InChI=1S/C10H10F3N/c11-10(12,13)8-2-1-6-4-9(14)5-7(6)3-8/h1-3,9H,4-5,14H2 N
  • Key:UBDQCUBRYLGYCL-UHFFFAOYSA-N N
 NY (what is this?)  (verify)

5-Trifluoromethyl-2-aminoindane (TAI) is a drug of the 2-aminoindane group with putative entactogenic effects. It functions as a selective serotonin releasing agent (SSRA). TAI is the aminoindane analogue of norfenfluramine and is approximately 50% as neurotoxic in comparison.[1]

References

  1. ^ Cozzi NV, Frescas S, Marona-Lewicka D, Huang X, Nichols DE (March 1998). "Indan analogs of fenfluramine and norfenfluramine have reduced neurotoxic potential". Pharmacology, Biochemistry, and Behavior. 59 (3): 709–15. doi:10.1016/S0091-3057(97)00557-1. PMID 9512076. S2CID 41048219.
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