Activin receptor

Activin types I and II receptor domain
Identifiers
SymbolActivin_recp
PfamPF01064
InterProIPR000472
PROSITEPDOC00223
SCOP21tbi / SCOPe / SUPFAM
Membranome1216
Available protein structures:
Pfam  structures / ECOD  
PDBRCSB PDB; PDBe; PDBj
PDBsumstructure summary

An Activin receptor is a receptor which binds activin. These proteins are receptor-type kinases of Ser/Thr type, which have a single transmembrane domain and a specific hydrophilic Cys-rich ligand-binding domain.[1][2][3]

Types include:

  • Activin type 1 receptors
  • Activin type 2 receptors

Human proteins containing this domain

ACVR1; ACVR1B; ACVR1C; ACVR2A; ACVR2B; ACVRL1; BMPR1A; BMPR1B; BMPR2; TGFBR1;

References

  1. ^ Wrana JL, Attisano L (1996). "Signal transduction by members of the transforming growth factor-beta superfamily". Cytokine Growth Factor Rev. 7 (4): 327–339. doi:10.1016/S1359-6101(96)00042-1. PMID 9023056.
  2. ^ Wrana JL, Attisano L, Wieser R, Ventura F, Massague J (1994). "Mechanism of activation of the TGF-beta receptor". Nature. 370 (6488): 341–347. doi:10.1038/370341a0. PMID 8047140. S2CID 4344481.
  3. ^ Massague J, Weis-Garcia F (1996). "Serine/threonine kinase receptors: mediators of transforming growth factor beta family signals". Cancer Surv. 27: 41–64. PMID 8909794.
  • Activin+receptors at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
This article incorporates text from the public domain Pfam and InterPro: IPR000472


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