Impentamine
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| Names
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| IUPAC name
5-(1H-imidazol-5-yl)pentan-1-amine
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| Identifiers
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CAS Number
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3D model (JSmol)
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| ChEMBL
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| ChemSpider
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| MeSH
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Impentamine
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| UNII
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InChI=1S/C8H15N3/c9-5-3-1-2-4-8-6-10-7-11-8/h6-7H,1-5,9H2,(H,10,11) N Key: MZCJWLAXZRFUPI-UHFFFAOYSA-N N InChI=1/C8H15N3/c9-5-3-1-2-4-8-6-10-7-11-8/h6-7H,1-5,9H2,(H,10,11) Key: MZCJWLAXZRFUPI-UHFFFAOYAF
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| Properties
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Chemical formula
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C8H15N3
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| Molar mass
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153.2248 g/mol
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Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references
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Impentamine is a histamine antagonist selective for the H3 subtype.[1][2]
References
- ^ Vollinga, RC; Menge, WM; Leurs, R; Timmerman, H (1995). "Homologs of histamine as histamine H3 receptor antagonists: a new potent and selective H3 antagonist, 4(5)-(5-aminopentyl)-1H-imidazole". Journal of Medicinal Chemistry. 38 (2): 266–71. doi:10.1021/jm00002a008. PMID 7830269.
- ^ Van Der Goot, H; Timmerman, H (2000). "Selective ligands as tools to study histamine receptors". European Journal of Medicinal Chemistry. 35 (1): 5–20. doi:10.1016/S0223-5234(00)00101-X. PMID 10733599.
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| H1 | | Agonists | |
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| Antagonists |
- Others: Atypical antipsychotics (e.g., aripiprazole, asenapine, brexpiprazole, brilaroxazine, clozapine, iloperidone, olanzapine, paliperidone, quetiapine, risperidone, ziprasidone, zotepine)
- Phenylpiperazine antidepressants (e.g., hydroxynefazodone, nefazodone, trazodone, triazoledione)
- Tetracyclic antidepressants (e.g., amoxapine, loxapine, maprotiline, mianserin, mirtazapine, oxaprotiline)
- Tricyclic antidepressants (e.g., amitriptyline, butriptyline, clomipramine, desipramine, dosulepin (dothiepin), doxepin, imipramine, iprindole, lofepramine, nortriptyline, protriptyline, trimipramine)
- Typical antipsychotics (e.g., chlorpromazine, flupenthixol, fluphenazine, loxapine, perphenazine, prochlorperazine, thioridazine, thiothixene)
- Unknown/unsorted: Azanator
- Belarizine
- Elbanizine
- Flotrenizine
- GSK1004723
- Napactadine
- Tagorizine
- Trelnarizine
- Trenizine
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| H2 | |
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| H3 | |
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| H4 | | Agonists |
- 4-Methylhistamine
- α-Methylhistamine
- Histamine
- L-Histidine
- OUP-16
- VUF-8430
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- See also
- Receptor/signaling modulators
- Monoamine metabolism modulators
- Monoamine reuptake inhibitors
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