Echinopsidine

Echinopsidine
Clinical data
Other namesEchinopsidine Iodide
Routes of
administration		Oral
ATC code
  • none
Legal status
Legal status
  • In general: ℞ (Prescription only)
Identifiers
IUPAC name
  • 1-Methyl-2,3-dihydroquinolin-4-imine
CAS Number
PubChem CID
ChemSpider
UNII
Chemical and physical data
FormulaC10H12N2
Molar mass160.220 g·mol−1

Echinopsidine (Adepren) is an antidepressant that was under development in Bulgaria for the treatment of depression.[1][2] It increases serotonin, norepinephrine, and dopamine levels in the brain and is believed to act as a monoamine oxidase inhibitor (MAOI).[3][4][5] Echinopsidine is found naturally in Echinops echinatus along with the related alkaloids echinopsine and echinozolinone.[6]

See also

References

  1. ^ Guliamov MG (1982). "[Experience with the use of new Bulgarian psychotropic drugs]". Zhurnal Nevropatologii I Psikhiatrii imeni S.S. Korsakova (in Russian). 82 (11): 115–122. PMID 6758442.
  2. ^ Guliamov MG (1986). "[Comparative evaluation of the therapeutic efficacy of the antidepressants adepren, linamiphen and emovit]". Zhurnal Nevropatologii I Psikhiatrii imeni S.S. Korsakova (in Russian). 86 (4): 582–587. PMID 3716711.
  3. ^ Tiutiulkova N, Gorancheva I (1978). "[Effect of adepren on the cerebral concentration of serotonin]". Eksperimentalna Meditsina I Morfologiia (in Bulgarian). 17 (2): 83–85. PMID 658004.
  4. ^ Stefanova D, Tiutiulkova N, Nikolova M (1976). "[Effect of adepren on the behavior and brain catecholamines of rats in an open field setup]". Eksperimentalna Meditsina I Morfologiia (in Bulgarian). 15 (1): 42–46. PMID 1269462.
  5. ^ Tiutiulkova NI, Gorancheva I (1975). "[Excretion of dopamine, noradrenaline, adrenaline, vanilmandelic acid and 5-hydroxyindoleacetic acid in the urine of volunteers treated with adepren]". Eksperimentalna Meditsina I Morfologiia (in Bulgarian). 14 (4): 187–189. PMID 1222713.
  6. ^ Khare CP (2007). "Echinops echinatus Roxb.". Indian Medicinal Plants An Illustrated Dictionary. Springer-Verlag Berlin Heidelberg. ISBN 978-0-387-70637-5.
This article is issued from Wikipedia. The text is available under Creative Commons Attribution-Share Alike 4.0 unless otherwise noted. Additional terms may apply for the media files.