5F-EDMB-PINACA

5F-EDMB-PINACA
Clinical data
Other names	5-Fluoro EDMB-PINACA
Legal status
Legal status	CA: Schedule II; DE: NpSG (Industrial and scientific use only); UK: Class B; US: Schedule I;
Identifiers
	IUPAC name Ethyl (S)-2-(1-(5-fluoropentyl)-1H-indazole-3-carboxamido)-3,3-dimethylbutanoate;
CAS Number	2504100-69-8 ;
PubChem CID	137700114;
ChemSpider	68004011;
UNII	UN52BPP7RB;
CompTox Dashboard (EPA)	DTXSID50963459 ;
Chemical and physical data
Formula	C21H30FN3O3
Molar mass	391.487 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES O=C(N[C@H](C(OCC)=O)C(C)(C)C)C1=NN(CCCCCF)C2=C1C=CC=C2;
	InChI InChI=1S/C21H30FN3O3/c1-5-28-20(27)18(21(2,3)4)23-19(26)17-15-11-7-8-12-16(15)25(24-17)14-10-6-9-13-22/h7-8,11-12,18H,5-6,9-10,13-14H2,1-4H3,(H,23,26)/t18-/m1/s1; Key:VDEACSPMBSUVRD-GOSISDBHSA-N;

5F-EDMB-PINACA is a designer drug and synthetic cannabinoid.^[1]^[2] In 2018, it was the fourth-most common synthetic cannabinoid identified in drugs seized by the Drug Enforcement Administration.^[3]

In the United States, 5F-EDMB-PINACA was temporarily emergency scheduled by the DEA in 2019.^[4] It was made a permanent Schedule I Controlled Substance on April 7, 2022.^[5]

References

^ Liu C, Jia W, Hua Z, Qian Z (2017). "Identification and analytical characterization of six synthetic cannabinoids NNL-3, 5F-NPB-22-7N , 5F-AKB-48-7N , 5F-EDMB-PINACA, EMB-FUBINACA, and EG-018". Drug Testing and Analysis. 9 (8): 1251–1261. doi:10.1002/dta.2160. PMID 28063270.
^ "5F-EDMB-PINACA" (PDF). NMS Labs.
^ "Emerging Threat Report: Annual 2018" (PDF). Special Testing and Research Laboratory, Drug Enforcement Administration. Archived from the original (PDF) on 2019-08-01. Retrieved 2019-08-03.
^ "Schedules of Controlled Substances: Temporary Placement of 5F-EDMB-PINACA, 5F-MDMB-PICA, FUB-AKB48, 5F-CUMYL-PINACA, and FUB-144 into Schedule I". Federal Register. 2019-04-16.
^ "Schedules of Controlled Substances: Placement of 5F-EDMB-PINACA, 5FMDMB-PICA, FUB-AKB48, 5F-CUMYLPINACA, and FUB-144 in Schedule I" (PDF). Federal Register. 87 (67). 2022-04-07.

[1] Liu C, Jia W, Hua Z, Qian Z (2017). "Identification and analytical characterization of six synthetic cannabinoids NNL-3, 5F-NPB-22-7N , 5F-AKB-48-7N , 5F-EDMB-PINACA, EMB-FUBINACA, and EG-018". Drug Testing and Analysis. 9 (8): 1251–1261. doi:10.1002/dta.2160. PMID 28063270.

[2] "5F-EDMB-PINACA" (PDF). NMS Labs.

[3] "Emerging Threat Report: Annual 2018" (PDF). Special Testing and Research Laboratory, Drug Enforcement Administration. Archived from the original (PDF) on 2019-08-01. Retrieved 2019-08-03.

[fedreg-Apr-2019-4] "Schedules of Controlled Substances: Temporary Placement of 5F-EDMB-PINACA, 5F-MDMB-PICA, FUB-AKB48, 5F-CUMYL-PINACA, and FUB-144 into Schedule I". Federal Register. 2019-04-16.

[5] "Schedules of Controlled Substances: Placement of 5F-EDMB-PINACA, 5FMDMB-PICA, FUB-AKB48, 5F-CUMYLPINACA, and FUB-144 in Schedule I" (PDF). Federal Register. 87 (67). 2022-04-07.

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