HU-320

HU-320
Identifiers
	IUPAC name (3S,4S)-3-[2,6-Dihydroxy-4-(2-methyloctan-2-yl)phenyl]-4-(prop-1-en-2-yl)cyclohex-1-ene-1-carboxylic acid;
CAS Number	380495-76-1 ;
PubChem CID	11223325;
ChemSpider	9398378 ;
CompTox Dashboard (EPA)	DTXSID001029794 ;
Chemical and physical data
Formula	C25H36O4
Molar mass	400.559 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES O=C(O)/C2=C/[C@H](c1c(O)cc(cc1O)C(C)(C)CCCCCC)[C@@H](\C(=C)C)CC2;
	InChI InChI=1S/C25H36O4/c1-6-7-8-9-12-25(4,5)18-14-21(26)23(22(27)15-18)20-13-17(24(28)29)10-11-19(20)16(2)3/h13-15,19-20,26-27H,2,6-12H2,1,3-5H3,(H,28,29)/t19-,20+/m1/s1 ; Key:LDMILSDGSQMZOB-UXHICEINSA-N ;
	(verify)

HU-320 (7-nor-7-carboxy-CBD-1,1-DMH) is a drug related to cannabidiol, which has strong antiinflammatory and immunosuppressive properties while demonstrating no psychoactive effects.^[1]^[2]

References

^ Sumariwalla PF, et al. (2004). "A novel synthetic, nonpsychoactive cannabinoid acid (HU-320) with antiinflammatory properties in murine collagen-induced arthritis". Arthritis Rheum. 50 (3): 985–998. doi:10.1002/art.20050. PMID 15022343.
^ Hanus LO, Tchilibon S, Ponde DE, Breuer A, Fride E, Mechoulam R (Mar 2005). "Enantiomeric cannabidiol derivatives: synthesis and binding to cannabinoid receptors". Org Biomol Chem. 3 (6): 1116–23. doi:10.1039/b416943c. PMID 15750656.